NFL Week 12 2025 schedule: Rams, Bucs, Bills and Cowboys all in action
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Week 12 of the 2025 NFL season will feature some notable matchups and the first start for a highly publicized rookie quarterback.
Los Angeles Rams quarterback Matthew Stafford will battle it out with Tampa Bay Buccaneers quarterback Baker Mayfield on Sunday night. The matchup will feature Stafford’s best player facing off against an up-and-coming quarterback in Mayfield. The NFC heavyweight title fight will likely be a matchup that fans will be looking forward to next January.
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Indianapolis Colts quarterback Daniel Jones throws a pass during the first half of an NFL football game against the Atlanta Falcons, Sunday, Nov. 9, 2025, in Berlin, Germany. (AP Photo/Martin Meissner)
One question fans constantly ask is: “Are the Indianapolis Colts real?” There would be no better way to prove that than against the cream of the AFC crop in the Kansas City Chiefs. Jonathan Taylor was also mentioned as an MVP candidate as he averages 113 yards per game.
Elsewhere, the Philadelphia Eagles face the Dallas Cowboys in a very important game for both teams. The Eagles have won this year, but questions have been raised about their struggling offense. Meanwhile, Dak Prescott is playing at an MVP level and will have a big test to see how true Dallas is in terms of playoff contenders.
Shedor Sanders will make his first NFL start at quarterback for the Cleveland Browns. He will have to deal with Las Vegas Raiders star Maxx Crosby who was in his face throughout the game.

Philadelphia Eagles quarterback Jalen Hurts (1) talks with teammates during the first half of an NFL football game against the Detroit Lions on Sunday, Nov. 16, 2025, in Philadelphia. (AP Photo/Matt Rourke)
Read below to see what the rest of the NFL schedule has to offer.
Thursday 20 November
Sunday 23 November
- Pittsburgh Steelers vs. Chicago Bears (1 p.m. ET)
- New England Patriots & Cincinnati Bengals (1 p.m. ET)
- New York Giants x Detroit Lions (1 p.m. ET)
- Minnesota Vikings x Green Bay Packers (1 p.m. ET)
- Seattle Seahawks vs. Tennessee Titans (1 p.m. ET)
- Indianapolis Colts vs. Kansas City Chiefs (1 p.m. ET)

Los Angeles Rams quarterback Matthew Stafford passes during the first half of an NFL football game against the Seattle Seahawks, Sunday, Nov. 16, 2025, in Inglewood, Calif. (AP Photo/Gregory Paul)

Tampa Bay Buccaneers running back Sean Tucker (44) celebrates with quarterback Baker Mayfield (6) after scoring a touchdown against the Buffalo Bills during the second half of an NFL football game, Sunday, Nov. 16, 2025, in Orchard Park, New York. (AP Photo/Jeffrey T. Barnes)
- New York Jets @ Baltimore Ravens (1 p.m. ET)
- Cleveland Browns vs. Las Vegas Raiders (4:05 p.m. ET)
- Jacksonville Jaguars vs. Arizona Cardinals (4:05 p.m. ET)
- Philadelphia Eagles x Dallas Cowboys (4:25 p.m. ET)
- Atlanta Falcons @ New Orleans Saints (4:25 p.m. ET)
- Tampa Bay Buccaneers @ Los Angeles Rams (8:20 p.m. ET)
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Monday 24 November
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