Scientists open how to kidnap the Zika virus our skin to be “mosquito magnet”

Zika, a virus of the mosquito transformer that was first identified in 1947 in the Makka Risos monkey, is still confused by scientists in several ways after about 80 years. While many people with Zika virus infection will not have symptoms, it is very dangerous to pregnant women. This is because the infection during pregnancy can cause small smallness, which is when the child’s head is much smaller than expected, and other congenital anomalies such as limbs of the ends, high muscle tone, eye abnormalities, and hearing loss. There is no treatment or vaccine.

While Zika has been reported in more than 90 countries, only little is known about what drives the transfer of Zika exactly. A new study published in Communications biology He explains that Zika causes metabolic changes in human skin that turns it from a barrier to mosquitoes, which enhances the scientific community’s understanding of the virus.

“The results we find that the Zika virus not only transmitted negatively, but it is actively manipulating human biology to ensure its survival.” He said in a media statement.

Fibry skin cells are responsible for maintaining your skin physiology and repairing the wound. But when Zika infection occurs, the new research found that instead of working as a preventive barrier that turns into a “mosquito magnet”, mosquitoes actually encourage the sting. It does this by changing the expression of the gene and protein from the fibrobiocytes. The researchers relied on a technique called national analysis, which studies the interaction of genes and proteins within the organism, to reach its conclusion.

Almost a decade ago, researchers are increasingly interested in studying Zika after a great outbreak in Brazil. The devastating epidemic produces an estimated 1.5 million infected, and more than 3,500 infants suffer from Microcatephaly by January 2016. While there has been no similar four -time, Zika is still a concern all over the world.

Recently, Zika’s infection was a rise in India, most of which was in Maharashtra state. While relevant cases of Microcephaly or Guilllain-Parre syndrome were not reported, the infection was the highest since 2021. The number of cases in pregnant women was unknown. the Global Health Organization He said, while the presence of Zika was not unusual, the increase in cases compared to previous years is not stereotype. Researchers are concerned that Zika cases will increase as a result of climate change. One study found that warming temperatures increase the risk of transition from 10 to 20 percent in Brazil over the next thirty yearsAnd another found that Climate change can bring Zika to Europe. As the world’s temperature rises, the areas where mosquitoes can multiply increased comfortably, stressing the need to develop treatments against Zika.

With the rise in cases of Zika and Paddle “The mosquitoes expand its scope, and to understand the mechanisms through which they acquire the feature of transmission, it can open new strategies to combat Arbovions.” “This can include the development of genetic interventions that disrupt the transmitted signal that appears to be very attractive to mosquitoes. The possibilities are interesting as they are urgent.”

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The study adds to the increasing research to improve the biological foundations of Zika, which may eventually lead to a vaccine or treatment. A study published in January in the magazine Mbio I found that the Zika virus hijacked a host protein called ankle2, which is a major protein in the development of the brain. Prien Shah, associate professor in the sections of microbiology, molecular heredity and chemical engineering at the University of California, Davis and a great writer in the newspaper, told the salon in an interview via the phone, that the research was the culmination of the research that started nearly a decade.

Shah said: “We have shown that the ankle 2 is really important to accelerate the repetition of the Zika virus in human cells, in a wide range of human cells, so hepatic neurons and even placenta cells, which are all the tissues that the Zika virus can afflict.” “We have also shown that the ankle 2 is important for repetition in mosquito cells, and we have shown that the second ankle is important to repeat other related viruses.”

This may be the basis for a vaccine or treatment in the future.

Shah said: “We know that the ankle 2 is important to repeat the viruses and that if we remove the ankle 2 of the cells using artificially freeing the genome, we can reduce the frequency of viruses.” “What would be really great is that if we can show that breaking this reaction, which we originally started is also important to repeat viruses.”

Shah said that if scientists can find a way to create specific mutations to break the protein reaction, this may be like progress in a future vaccine – but it is difficult to solve.

“I think it will be likely,” Shah said.